dc.contributor.author | Fernández Martínez, Tomas Eduardo | es |
dc.date.accessioned | 2014-06-20T22:17:27Z | |
dc.date.available | 2014-06-20T22:17:27Z | |
dc.date.issued | 2012 | es |
dc.identifier.citation | Ponce-Monter, H., Ortiz, M.I., Garza-Hernández, A.F., Monroy-Maya, R., Soto-Ríos, M., Carrillo-Alarcón, L., Reyes-García, G., Fernández-Martínez, E. (2012). Effect of diclofenac with B vitamins for the treatment of acute pain originated by lower-limb fracture and surgery. Pain Research and Treatment, article ID 104782. | es |
dc.identifier.uri | https://repository.uaeh.edu.mx/bitstream/handle/123456789/15150 | |
dc.description.abstract | The aim of this study was to compare the efficacy of diclofenac, for the treatment of acute pain originated by lower-limb fracture and surgery, with that of diclofenac plus B vitamins. This was a single-center, prospective, randomized and double-blinded clinical trial. Patients with lower-limb closed fractures rated their pain on a 10-cm visual analog scale (VAS). Patients were then randomized to receive diclofenac or diclofenac plus B vitamins (thiamine, pyridoxine and cyanocobalamin) intramuscularly twice daily. Patient evaluations of pain intensity were recorded throughout two periods: twenty-four hours pre-surgery and twenty-four hours post-surgically. One hundred twenty-two patients completed the study. The subjects? assessments of limb pain on the VAS showed a significant reduction from baseline values regardless of the treatment group. Diclofenac plus B vitamins combination was more effective to reduce the pain than diclofenac alone. The results showed that the addition of B vitamins to diclofenac increased its analgesic effect. | es |
dc.language | es | es |
dc.subject | Farmacología de la Reproducción y Analgesia inducida por neuroesteroides y AINES | es |
dc.title | Effect of diclofenac with B vitamins for the treatment of acute pain originated by lower-limb fracture and surgery. | es |
dc.type | Article | es |