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ACEMETACIN ANTINOCICEPTIVE MECHANISM IS NOT RELATED TO NO OR K+ CHANNEL PATHWAYS
(2010)
Indomethacin is a nonsteroidal anti-inflammatory drug (NSAID) used for the treatment of acute gout and inflammation. However, its use is limited due to side effects. Acemetacin is a prodrug of indomethacin that exhibits ...
Primary dysmenorrhea among Mexican university students: prevalence, impact and treatment
(2010)
Objective: To evaluate the prevalence, impact and treatment of primary dysmenorrhea among Mexican university students. Study design: A multiple-choice questionnaire was administered to 1539 students in six university ...
Pharmacokinetic pharmacodynamic modelling of the analgesic effects of lumiracoxib, a selective inhibitor of cyclooxygenase-2, in ratsbph
(2010)
This study establishes a pharmacokinetic/pharmacodynamic (PK/PD) model to describe the time course and in vivo mechanisms of action of the antinociceptive effects of lumiracoxib, evaluated by the thermal hyperalgesia test in rats.
Spasmolytic and anti-inflammatory effects of Aloysia triphylla and citral, in vitro and in vivo studies.
(2010)
Aloysia triphylla is traditionally utilized for the treatment of menstrual colic (primary dysmenorrhea) in Mexico. Citral is the main chemical component found in Aloysia triphylla leaves extract. Primary dysmenorrhea is a ...