Browsing by Author "Sánchez Gutiérrez, Manuel"
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Antinociceptive, genotoxic and histopathological study of Heliopsis longipes S.F. Blake in mice
Sánchez Gutiérrez, Manuel (2010)Ethnopharmacological relevance: H. longipes S.F. Blake (Asteraceae) is a Mexican plant, whose roots aretraditionally used as a condiment, as a mouth anesthetic, and as an antiparasitic. Affinin is the alkamidepresent in ... -
Cytotoxic and Antiproliferative Effect of Tepary Bean Lectins on C33-A, MCF-7, SKNSH, and SW480 Cell Lines
Sánchez Gutiérrez, Manuel (2014)For many years, several studies have been employing lectin from vegetables in order to prove its toxic effect on various cell lines. In this work, we analyzed the cytotoxic, antiproliferative, and post-incubatory effect ... -
Decreased in vitro fertility in male rats exposed to fluoride-induced oxidative stress damage and mitochondrial transmembrane potential loss
Sánchez Gutiérrez, Manuel (2008)Fluorosis, caused by drinking water contamination with inorganic fluoride, is a public health problem inmany areas around the world. The aim of the study was to evaluate the effect of environmentally relevantdoses of ... -
Effect of dietary selenium deficiency on the in vitro fertilizing ability of mice spermatozoa
Sánchez Gutiérrez, Manuel (2008)Selenium is an essential micronutrient formammals, being integral part of antioxidant system.The aim of the study was to evaluate the effect ofselenium deficiency on in vitro fertilization (IVF)capacity of spermatozoa and ... -
Effectiveness of Diclofenac, Ketorolac and Etoricoxib in the Treatment of Acute Pain from Ankle Fracture
Sánchez Gutiérrez, Manuel (2010)Tissue degeneration, infection, inflammation, cancer, trauma, surgery and limb fractures all produce pain. Each of these physiological abnormalities requires a therapeutic approach different from the last. In acute pain, ... -
Exposure to bisphenol A in young adult mice does not alter ovulation but does alter the fertilization ability of oocytes
Sánchez Gutiérrez, Manuel (2015)"Follicle growth culminates in ovulation, which allows for the expulsion of fertilizable oocytes and the formation of corpora lutea. Bisphenol A (BPA) is present in many consumer products, and it has been suggested that ... -
Farmacocinética Antiepiléptico
Sánchez Gutiérrez, Manuel (2011-01)This presentation is a part of the course “Basic Pharmacology” imparted in the Academic Area of Medicine, Institute of Health Sciences at the Autonomous University of the State of Hidalgo. Period January – June 2011. ... -
Farmacocinética Integral
Sánchez Gutiérrez, Manuel (2011-01)This presentation is a part of the curse “Basic Pharmacology” imparted in the Medicine Academic Area, Health Sciences Institute of the Universidad Autónoma del Estado de Hidalgo July – December 2011. Pharmacokinetics ... -
Investigation on the Protective Effect of ?-Mannan against the DNA Damage Induced by Aflatoxin B1 in Mouse Hepatocytes
Sánchez Gutiérrez, Manuel (2009)Aflatoxin B1 is a contaminant of agricultural and dairy products that can berelated to mutagenic and carcinogenic effects. In this report we explore the capacity of ?-mannan (Man) to reduce the DNA damage induced by AFB1 ... -
Methamidophos alters sperm function and DNA at different stages of spermatogenesis in mice
Sánchez Gutiérrez, Manuel (2014)Methamidophos (MET) is a highly toxic organophosphate (OP) pesticide that is widely used in developing countries. MET has male reproductive effects, including decreased fertility. We evaluated MET effects on sperm quality, ... -
Methyl-parathion decreases sperm function and fertilization capacity after targeting spermatocytes and maturing spermatozoa
Sánchez Gutiérrez, Manuel (2009)Paternal germline exposure to organophosphorous pesticides (OP) has been associated with reproductivefailures and adverse effects in the offspring. Methyl-parathion (Me-Pa), a worldwide-used OP, hasreproductive adverse ... -
NADPH oxidase participates in the oxidative damage caused by fluoride in rat spermatozoa. Protective role of a-tocopherol
Sánchez Gutiérrez, Manuel (2011) -
Pharmacological Interaction between Gabapentin and Glibenclamide in the Formalin Test in the Diabetic Rat
Sánchez Gutiérrez, Manuel (2010)There is evidence that local peripheral administration of gabapentin produces antinociception through the activation of the ATP-sensitive K+-channel. However, this interaction has not been evaluated systemically, nor in ... -
Pharmacovigilance of Psychoactive Medications in a Mexican Psychiatric Hospital
Sánchez Gutiérrez, Manuel (2010)Pharmacovigilance is the permanent collection and assessment of the safety data of drugs in the interest of precise knowledge of the safety profile. We monitored notifications of suspected adverse reactions (AR) produced ... -
Presence, processing, and localization of mouse ADAM15 during sperm maturation and the role of its disintegrin domain during sperm egg binding
Sánchez Gutiérrez, Manuel (2008)Successful fertilization requires gametes to complete several stages, beginning with maturation and transport along the male and femalereproductive tracts and ending with the interaction between the sperm and the egg. This ... -
Prevention of Aflatoxin B?-Induced DNA Breaks by ?-D-Glucan
Sánchez Gutiérrez, Manuel (2015)"Aflatoxins are a group of naturally-occurring carcinogens that are known to contaminate different human and animal foodstuffs. Aflatoxin B1 (AFB1) is the most genotoxic hepatocarcinogenic compound of all of the aflatoxins. ... -
Protective Effect of Resveratrol on Biomarkers of Oxidative Stress Induced by Iron/Ascorbate in Mouse Spermatozoa
Sánchez Gutiérrez, Manuel (2014)Resveratrol (RVT) is a polyphenolic compound found mainly in the grape and attributed with various pharmacological properties, among them their antioxidant activity. In the present study, we assess the antioxidant activity ... -
Quimioprevención de fitoquímicos
Sánchez Gutiérrez, Manuel (2009)