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Antinociceptive, genotoxic and histopathological study of Heliopsis longipes S.F. Blake in mice
(2010)
Ethnopharmacological relevance: H. longipes S.F. Blake (Asteraceae) is a Mexican plant, whose roots aretraditionally used as a condiment, as a mouth anesthetic, and as an antiparasitic. Affinin is the alkamidepresent in ...
Decreased in vitro fertility in male rats exposed to fluoride-induced oxidative stress damage and mitochondrial transmembrane potential loss
(2008)
Fluorosis, caused by drinking water contamination with inorganic fluoride, is a public health problem inmany areas around the world. The aim of the study was to evaluate the effect of environmentally relevantdoses of ...
Exposure to Sodium Fluoride Produces Signs of Apoptosis in Rat Leukocytes
(2010)
Fluoride is naturally present in the earth's crust and can be found in rocks, coal, and clay; thus, it can be found in small quantities in water, air, plants, and animals. Therefore, humans are exposed to fluoride through ...
In vivo extracellular matrix protein expression by human periodontal ligament after stimulation with orthodontic force
(2010)
It is well known that the orthodontic force applied to teeth generates a series of events that remodel theperiodontal ligament (PDL). Extracellular matrix proteins (ECM) are described as molecular regulatorsof these events. ...
Investigation on the Protective Effect of ?-Mannan against the DNA Damage Induced by Aflatoxin B1 in Mouse Hepatocytes
(2009)
Aflatoxin B1 is a contaminant of agricultural and dairy products that can berelated to mutagenic and carcinogenic effects. In this report we explore the capacity of ?-mannan (Man) to reduce the DNA damage induced by AFB1 ...
Investigation on the Protective Effect of ?-Mannan against the DNA Damage Induced by Aflatoxin B1 in Mouse Hepatocytes
(2009)
Aflatoxin B1 is a contaminant of agricultural and dairy products that can berelated to mutagenic and carcinogenic effects. In this report we explore the capacity of ?-mannan (Man) to reduce the DNA damage induced by AFB1 ...
Pharmacokinetic pharmacodynamic modelling of the analgesic effects of lumiracoxib, a selective inhibitor of cyclooxygenase-2, in ratsbph
(2010)
This study establishes a pharmacokinetic/pharmacodynamic (PK/PD) model to describe the time course and in vivo mechanisms of action of the antinociceptive effects of lumiracoxib, evaluated by the thermal hyperalgesia test in rats.
Hepatoprotective effects of glycine and vitamin E, during the early phase of liver regeneration in the rat
(2009)
Our objective was to demonstrate the protective effect of glycine (Gly) and vitamin E (VE) on a model ofethanol-induced acute liver injury during the early phase of liver regeneration after partial hepatectomy(PH) in rats. ...
Effect of Naringin on the DNA Damage Induced by Daunorubicin in Mouse Hepatocytes and Cardiocytes
(2010)
Naringin (Nar) is a flavonoid that has shown antigenotoxic effect against the chromosome damage inducedby various compounds. The aims of the present investigation on Nar were threefold: a) to determine its DNAbreaking ...