Universidad Autónoma del Estado de Hidalgo
    • English
    • español
  • English 
    • English
    • español
  • Login
View Item 
  •   RIA-UAEH Home
  • Ciencias de la Salud
  • Medicina
  • Artículos arbitrados
  • View Item
  •   RIA-UAEH Home
  • Ciencias de la Salud
  • Medicina
  • Artículos arbitrados
  • View Item
JavaScript is disabled for your browser. Some features of this site may not work without it.

Detection of Cytotoxic Activity of Lectin on Human Colon Adenocarcinoma (Sw480) and Epithelial Cervical Carcinoma (C33-A)

Thumbnail
View/Open
2.pdf (238.4Kb)
Date
2011
Author
Valadez Vega, María del Carmen
Metadata
Show full item record
Abstract
Lectins comprise a heterogeneous class of proteins that recognize thecarbohydrate moieties of glycoconjugates with high specificity. Numerous studies haveOPEN ACCESSMolecules 2011, 162108shown that lectins are capable of recognizing specific carbohydrate moieties displayed bymalignant cells or tissues. The present work was performed to investigate the effects oftepary bean (Phaseolus acutifolius) lectins on proliferation, colony formation, andalteration of DNA synthesis of human malignant cells. Tepary bean lectin showed dosedependent effects on the inhibition of viability as well as on colony formation in twohuman malignant cells lines (C33-A, Sw480); By contrast, tepary bean lectin only showedsignificant effects on DNA synthesis on Sw480 cells. Our results provide evidence of theanti- proliferative and cytotoxic effects of the tepary bean lectins on C33-A and Sw480cells lines.
URI
https://repository.uaeh.edu.mx/bitstream/handle/123456789/11938
Collections
  • Artículos arbitrados

DSpace software copyright © 2002-2015  DuraSpace
Contact Us | Send Feedback

Licencia Creative Commons
Esta obra está bajo una Licencia Creative Commons Atribución-NoComercial-SinDerivar 4.0 Internacional.

Theme by 
@mire NV
 

 

Browse

All of RIA-UAEHCommunities & CollectionsBy Issue DateAuthorsTitlesSubjectsThis CollectionBy Issue DateAuthorsTitlesSubjects

My Account

Login

Statistics

View Usage Statistics

DSpace software copyright © 2002-2015  DuraSpace
Contact Us | Send Feedback

Licencia Creative Commons
Esta obra está bajo una Licencia Creative Commons Atribución-NoComercial-SinDerivar 4.0 Internacional.

Theme by 
@mire NV