La importancia de la biotecnología en las ciencias de la salud: una revisión

Palabras clave: Biotecnología, salud, alimentación, ambiente

Resumen

La biotecnología es un campo interdisciplinario, en el que, se utilizan diversas metodologías y herramientas enfocados en la transformación de organismos vivos o sustancias derivadas de dichos organismos que pueden ser dirigidos a alguna problemática específica.

Por una parte la biotecnología puede ayudar a introducir características fenotípicas y genotípicas en los cultivos, lo que permiten la producción de alimentos enriquecidos con nutrientes pudiendo ayudar a la diminución de la desnutrición en la población susceptible, además de involucrar las bases biotecnologías en la generación de técnicas de pronóstico y diagnostico tanto en enfermedades no transmitibles, como en enfermedades en los que se encuentran involucrados algún agente infeccioso, ya sea que hablemos de generación de proteínas recombinantes, vacunas y técnicas de diagnóstico molecular, que resumido podemos hablar de la estabilidad y/o recuperación de la salud de la población.

Otro campo importante de la biotecnología es el uso de microorganismos y la biorremedación de suelos, agua, residuos, etc.

Por lo que, en este manuscrito presenta una revisión sobre los aportes de la biotecnología en el campo de las ciencias de la salud, mediante el desarrollo de herramientas de cultivos modificados genéticamente enriquecidos nutricionalmente, diagnóstico molecular, vacunas, y gestión de desechos.

 

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Gupta, V., Sengupta, M., Prakash, J., & Tripathy, B. C. (2016). An Introduction to Biotechnology. Basic and Applied Aspects of Biotechnology, 1–21. https://doi.org/10.1007/978-981-10-0875-7_1

World Health Organization. (2021). Malnutrition. Retrieved September 5, 2022, from https://www.who.int/news-room/fact-sheets/detail/malnutrition

Ghosh, S., Datta, K., & Datta, S. K. (2019). 7 - Rice vitamins. In J. Bao (Ed.), Rice (Fourth Edition) (pp. 195–220). AACC International Press. https://doi.org/10.1016/B978-0-12-811508-4.00007-1

Lucca, P., Hurrell, R., & Potrykus, I. (2002). Fighting Iron Deficiency Anemia with Iron-Rich Rice. Journal of the American College of Nutrition, 21(sup3), 184S-190S. https://doi.org/10.1080/07315724.2002.10719264.

Manjeru P, Van Biljon A, Labuschagne M. (2019) The development and release of maize fortified with provitamin A carotenoids in developing countries. Crit Rev Food Sci Nutr.59(8):1284-1293. doi: 10.1080/10408398.2017.1402751

Paine JA, Shipton CA, Chaggar S, Howells RM, Kennedy MJ, Vernon G, Wright SY, Hinchliffe E, Adams JL, Silverstone AL, Drake R. (2005). Improving the nutritional value of Golden Rice through increased pro-vitamin A content. Nat Biotechnol.;23(4):482-7. doi: 10.1038/nbt1082.

Timoneda J, Rodríguez-Fernández L, Zaragozá R, Marín MP, Cabezuelo MT, Torres L, Viña JR, Barber T. (2018).Vitamin A Deficiency and the Lung. Nutrients. 21;10(9):1132. doi: 10.3390/nu10091132.

Botella-Pavía, P., & Rodríguez-Concepción, M. (2006). Carotenoid biotechnology in plants for nutritionally improved foods. Physiologia Plantarum, 126(3), 369–381. https://doi.org/10.1111/j.1399-3054.2006.00632.x

Chakauya, E., Coxon, K. M., Whitney, H. M., Ashurst, J. L., Abell, C., & Smith, A. G. (2006). Pantothenate biosynthesis in higher plants: advances and challenges. Physiologia Plantarum, 126(3), 319–329. https://doi.org/10.1111/j.1399-3054.2006.00683.x

Ishikawa, T., Dowdle, J., & Smirnoff, N. (2006). Progress in manipulating ascorbic acid biosynthesis and accumulation in plants. Physiologia Plantarum, 126(3), 343–355. https://doi.org/10.1111/j.1399-3054.2006.00640.x

Zimmermann, M. B., & Boelaert, K. (2015). Iodine deficiency and thyroid disorders. The Lancet. Diabetes & Endocrinology, 3(4), 286–295. https://doi.org/10.1016/S2213-8587(14)70225-6

Organización Mundial de la Salud. (2020). Las 10 principales causas de muerte. Retrieved March 31, 2021, from https://www.who.int/news-room/fact-sheets/detail/the-top-10-causes-of-death

World Health Organization. (n.d.). Enfermedades Transmisibles - OPS/OMS | Organización Panamericana de la Salud. Retrieved September 5, 2022, from https://www.paho.org/es/temas/enfermedades-transmisibles

Daar, A. S., Thorsteinsdóttir, H., Martin, D. K., Smith, A. C., Nast, S., & Singer, P. A. (2002). Top ten biotechnologies for improving health in developing countries. Nature Genetics, 32(2), 229–232. https://doi.org/10.1038/ng1002-229

Akhtar, S., Nasir, J. A., & Hinde, A. (2020). The prevalence of hepatitis C virus infection in β-thalassemia patients in Pakistan: a systematic review and meta-analysis. BMC Public Health, 20(1), 587. https://doi.org/10.1186/s12889-020-8414-5

Louie, A. Y., Hüber, M. M., Ahrens, E. T., Rothbächer, U., Moats, R., Jacobs, R. E., … Meade, T. J. (2000). In vivo visualization of gene expression using magnetic resonance imaging. Nature Biotechnology, 18(3), 321–325. https://doi.org/10.1038/73780

Afzal, A. (2020). Molecular diagnostic technologies for COVID-19: Limitations and challenges. Journal of Advanced Research, 26, 149–159. https://doi.org/10.1016/j.jare.2020.08.002

Palmer, C. J., Lindo, J. F., Klaskala, W. I., Quesada, J. A., Kaminsky, R., Baum, M. K., & Ager, A. L. (1998). Evaluation of the OptiMAL test for rapid diagnosis of Plasmodium vivax and Plasmodium falciparum malaria. Journal of Clinical Microbiology, 36(1), 203–206. https://doi.org/10.1128/JCM.36.1.203-206.1998

Bumgarner, R. (2013). Overview of DNA microarrays: types, applications, and their future. Current Protocols in Molecular Biology, Chapter 22, Unit 22.1. https://doi.org/10.1002/0471142727.mb2201s101

Li, Z., Dong, P., Ren, M., Song, Y., Qian, X., Yang, Y., … Liu, F. (2016). PD-L1 Expression Is Associated with Tumor FOXP3+ Regulatory T-Cell Infiltration of Breast Cancer and Poor Prognosis of Patient. Journal of Cancer, 7(7), 784–793. https://doi.org/10.7150/jca.14549

Walsh, G. (2003). Pharmaceutical biotechnology products approved within the European Union. European Journal of Pharmaceutics and Biopharmaceutics, 55(1), 3–10. https://doi.org/10.1016/S0939-6411(02)00165-0

Dingermann, T. (2008). Recombinant therapeutic proteins: production platforms and challenges. Biotechnology Journal, 3(1), 90–97. https://doi.org/10.1002/biot.200700214

Graumann, K., & Premstaller, A. (2006). Manufacturing of recombinant therapeutic proteins in microbial systems. Biotechnology Journal, 1(2), 164–186. https://doi.org/10.1002/biot.200500051

Daud, S., Shahzad, S., Shafique, M., Bhinder, M. A., Niaz, M., Naeem, A., … Husnain, T. (2014). Optimization and Validation of PCR protocol for three Hypervariable Regions (HVI, HVII and HVIII) in Human Mitochondrial DNA. Advancements in Life Sciences, 1(3), 165–170.

Baker, B. K. (2016). Trans-Pacific Partnership Provisions in Intellectual Property, Transparency, and Investment Chapters Threaten Access to Medicines in the US and Elsewhere. PLOS Medicine, 13(3), e1001970. https://doi.org/10.1371/journal.pmed.1001970

Gessner, B. D., Kaslow, D., Louis, J., Neuzil, K., O’Brien, K. L., Picot, V., … Nelson, C. B. (2017). Estimating the full public health value of vaccination. Vaccine, 35(46), 6255–6263. https://doi.org/10.1016/j.vaccine.2017.09.048

Shaker, M., Phillips, E., Blumenthal, K. G., Abrams, E. M., Banerji, A., Oppenheimer, J., … Greenhawt, M. (2021). The Importance of a Timely Second Dose of the 2021 COVID-19 mRNA Vaccine Depends on the Protection Afforded by a First Dose and Subsequent Risk of Anaphylaxis. The Journal of Allergy and Clinical Immunology. In Practice, 9(7), 2556–2561. https://doi.org/10.1016/j.jaip.2021.04.015

Nascimento, I. P., & Leite, L. C. C. (2012). Recombinant vaccines and the development of new vaccine strategies. Brazilian Journal of Medical and Biological Research = Revista Brasileira De Pesquisas Medicas E Biologicas, 45(12), 1102–1111. https://doi.org/10.1590/s0100-879x2012007500142

Pollet, J., Chen, W.-H., & Strych, U. (2021). Recombinant protein vaccines, a proven approach against coronavirus pandemics. Advanced Drug Delivery Reviews, 170, 71–82. https://doi.org/10.1016/j.addr.2021.01.001

Ada, G. (2005). Overview of vaccines and vaccination. Molecular Biotechnology, 29(3), 255–272. https://doi.org/10.1385/MB:29:3:255

Zhang, L., Wang, W., & Wang, S. (2015). Effect of vaccine administration modality on immunogenicity and efficacy. Expert Review of Vaccines, 14(11), 1509–1523. https://doi.org/10.1586/14760584.2015.1081067

Dua, M., Singh, A., Sethunathan, N., & Johri, A. K. (2002). Biotechnology and bioremediation: successes and limitations. Applied Microbiology and Biotechnology, 59(2–3), 143–152. https://doi.org/10.1007/s00253-002-1024-6

Watanabe, K. (2001). Microorganisms relevant to bioremediation. Current Opinion in Biotechnology, 12(3), 237–241. https://doi.org/10.1016/S0958-1669(00)00205-6

Kapahi, M., & Sachdeva, S. (2019). Bioremediation Options for Heavy Metal Pollution. Journal of Health & Pollution, 9(24), 191203. https://doi.org/10.5696/2156-9614-9.24.191203

Kour, D., Kaur, T., Devi, R., Yadav, A., Singh, M., Joshi, D., Saxena, A. K. (2021). Beneficial microbiomes for bioremediation of diverse contaminated environments for environmental sustainability: present status and future challenges. Environmental Science and Pollution Research International, 28(20), 24917–24939. https://doi.org/10.1007/s11356-021-13252-7

Ito, A., Takachi, T., Aizawa, J., & Umita, T. (2001). Chemical and biological removal of arsenic from sewage sludge. Water Science and Technology, 44(10), 59–64. https://doi.org/10.2166/wst.2001.0581

Akash, S., Sivaprakash, B., Rajamohan, N., Pandiyan, C. M., & Vo, D.-V. N. (2022). Pesticide pollutants in the environment – A critical review on remediation techniques, mechanism and toxicological impact. Chemosphere, 301, 134754. https://doi.org/10.1016/j.chemosphere.2022.134754

Hamoda, M. F. (2006). Air pollutants emissions from waste treatment and disposal facilities. Journal of Environmental Science and Health. Part A, Toxic/Hazardous Substances & Environmental Engineering, 41(1), 77–85. https://doi.org/10.1080/10934520500298895

Watson, R. E., Jacobson, C. F., Williams, A. L., Howard, W. B., & DeSesso, J. M. (2006). Trichloroethylene-contaminated drinking water and congenital heart defects: A critical analysis of the literature. Reproductive Toxicology, 21(2), 117–147. https://doi.org/10.1016/j.reprotox.2005.07.013

Head, I. M., & Swannell, R. P. (1999). Bioremediation of petroleum hydrocarbon contaminants in marine habitats. Current Opinion in Biotechnology, 10(3), 234–239. https://doi.org/10.1016/S0958-1669(99)80041-X

Publicado
2023-01-05
Cómo citar
Campos-Flores, J. R., Hernández-Trejo , A., & Orbe Orihuela, Y. C. (2023). La importancia de la biotecnología en las ciencias de la salud: una revisión. XIKUA Boletín Científico De La Escuela Superior De Tlahuelilpan, 11(21), 4-8. https://doi.org/10.29057/xikua.v11i21.9923
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