Revisión del efecto de la vitamina E sobre biomarcadores inflamatorios asociados a la obesidad
Resumen
Introducción: La vitamina E es un nutriente esencial y en la naturaleza existe en diversas isoformas, y debido a su isoforma, el α-tocoferol (15 mg/día) presenta una mayor actividad antioxidante, evitando la peroxidación lipídica, así como un efecto antiinflamatorio al disminuir y/o inhibir la liberación de sustancias proinflamatorias (PCR, TNF-α e IL-6) secretadas por el tejido adiposo en la obesidad. Objetivo: Recopilar información acerca del efecto de la vitamina E sobre los biomarcadores inflamatorios asociados a la obesidad. Material y métodos: Se realizó una revisión bibliográfica a través de bases de datos electrónicas. Resultados: Con base en 16 artículos, se encontró que la ingesta de vitamina E a concentraciones de 372.50 UI/día a 1500 UI/día disminuyen significativamente los niveles de proteína C reactiva (PCR), TNF-α e IL-6. Conclusión: La vitamina E a una concentración de 400 UI/día ejerce un efecto inhibidor en los niveles de biomarcadores inflamatorios asociados a la obesidad.
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