Revisión del efecto de la vitamina E sobre biomarcadores inflamatorios asociados a la obesidad

Palabras clave: inflamación, tocoferol, vitamina E

Resumen

Introducción: La vitamina E es un nutriente esencial y en la naturaleza existe en diversas isoformas, y debido a su isoforma, el α-tocoferol (15 mg/día) presenta una mayor actividad antioxidante, evitando la peroxidación lipídica, así como un efecto antiinflamatorio al disminuir y/o inhibir la liberación de sustancias proinflamatorias (PCR, TNF-α e IL-6) secretadas por el tejido adiposo en la obesidad. Objetivo: Recopilar información acerca del efecto de la vitamina E sobre los biomarcadores inflamatorios asociados a la obesidad. Material y métodos: Se realizó una revisión bibliográfica a través de bases de datos electrónicas. Resultados: Con base en 16 artículos, se encontró que la ingesta de vitamina E a concentraciones de 372.50 UI/día a 1500 UI/día disminuyen significativamente los niveles de proteína C reactiva (PCR), TNF-α e IL-6.  Conclusión: La vitamina E a una concentración de 400 UI/día ejerce un efecto inhibidor en los niveles de biomarcadores inflamatorios asociados a la obesidad.

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Zhao L, Fang X, Marshall M, Chung S. Regulation of obesity and metabolic complications by gamma and delta Tocotrienols. Molecules 2016; 21(3): 344.

Shamah-Levy T, Vielma-Orozco E, Heredia-Hernández O, Romero-Martínez M, Mojica-Cuevas J, Cuevas-Nasu L, Santaella-Castell JA, Rivera-Dommarco J. Encuesta Nacional de Salud y Nutrición 2018-19: Resultados Nacionales. Cuernavaca, México: Instituto Nacional de Salud Pública, 2020.

Ellulu MS, Patimah I, Khaza'ai H, Rahmat A, Abed Y. Obesity and inflammation: the link mechanism and complications. Archivos de ciencia médica 2017, 13(4): 851–863.

Lovati AB, Bottagisio M, Maraldi S, Violatto MB, Bortolin M, De Vecchi E, Bigini P, Drago L, Romanò CL. Vitamin E Phosphate Coating Stimulates Bone Deposition in Implant-related Infections in a Rat Model. Clin. Orthop. Relat. Res. 2018; 476 (6):1324-1338.

Abraham A, Kattor A, Saldeen T, Mehta J. Vitamin E and its anticancer effects. Crit Rev Food Sci Nutr 2018; 59 (17): 2831-2838.

Magariño M, Mateo CM, Nolasco SM. Kinetics of tocopherol degradation during the storage of wheat germ oil. Can. J. Chem 2015; 93 (11): 1999-2004.

Gedi MA, Briars R, Yuseli F, Zainol N, Darwish R, Salter AM, Gray DA. Component analysis of nutritionally rich chloroplasts: recovery from conventional and unconventional Green plant species. J. Food Sci. Technol. 2017; 54(9): 2746-2757.

Meydani S, Lewis E, Wu D. Should vitamin E recommendations for older adults be increased?. Adv Nutr 2018; 9 (5): 533-543.

Reboul E. Vitamin E Bioavailability: Mechanisms of Intestinal Absorption in the Spotlight. Antioxidants 2017; 6(4): 95. (5)

Mazur E, Litch N. Lutz’s nutrition and diet therapy. En: Vitamins. 7th ed. Philadelphia: F.A. Davis Company; 2018: 78-79.

Yuan P, Cui S, Liu Y, Li J, Du G, Liu L. (2020). Metabolic engineering for the production of fat-soluble vitamins: advances and perspectives. Appl. Microbiol. Biotechnol. 2020; 104 (3): 935-951.

Gay MA. Nutrición. En: Alimentos y su composición. España: Ministerio de educación y formación profesional; 2018: 14.

Pasias I, Kiriakou I, Papakonstantinou L, Proestos C. Determination of Vitamin E in cereal products and biscuits by GC-FID. Foods 2018; 7 (3): 1-6.

Sában J. Control global del riesgo cardiometabólico II: La disfunción endotelial como diana preferencial. En: Análisis crítico de la suplementación con antioxidantes. Madrid, España: Ediciones Díaz de Santos; 2017:781-782.

Gesteiro E, Galera J, González M. Aceite de palma y salud cardiovascular: consideraciones para valorar la literatura. Nutr Hosp 2018; 35(5): 1229-1242.

Shahidi F, Costa de Camargo, A. Tocopherols and tocotrienols in common and emerging dietary sources: Occurrence, Applications, and Health Benefits. Int. J. Mol. Sci. 2016; 17(10): 1745.

Granda L, Rosero A, Benešová K, Pluháčková H, Neuwirthová, J, Cerkal, R. Content of Selected Vitamins and Antioxidants in Colored and nonpigmented varieties of quinoa, Barley, and Wheat Grains. J. Food Sci. 2018; 83(10): 2439-2447.

Schmölz L, Birringer M, Lorkowski S, Wallert M. Complexity of vitamin E metabolism. World J. Biol Chem. 2016, 7(1): 14-43.

Jiang Q. Natural forms of Vitamin E as effective agents for cancer prevention and therapy. Adv Nutr 2017, 8(6): 850-867.

McBurney MI, Yu EA, Ciappio ED, Bird JK, Eggersdorfer M, Mehta S. Suboptimal Serum α-Tocopherol concentrations observed among younger adults and those depending exclusively upon food sources, NHANES 2003-2006. PLOS ONE 2015, 10(8): e0135510.

Schett G, Neurath MF. Resolution of chronic inflammatory disease: universal and tissue-specific concepts. Nat. Commun 2018, 9: 3261.

Krüger K. Inflammation during Obesity-Pathophysiological concepts and effects of physical activity. Dtsch. Z. Sportmed. 2017, 68:163-169.

Castoldi A, Naffah de Souza C, Câmara NOS, Moraes-Vieira PM. The macrophage switch in obesity development. Front. Immunol. 2016, 6: 1-11.

Masschelin PM, Cox AR, Chernis N, Hartig SM. The impact of oxidative stress on adipose tissue energy balance. Front. Physiol. 2020, 10: 1-8.

Calvo BS, Gómez CC, López NC, López BP. Manual de Alimentación. Planificación alimentaria. En: Santamaria JB, Valero PM, Alarcón QN, Palma MS, López PB, Gómez CC, editors. Los nutrientes: vitaminas minerales y oligoelementos. Madrid. Editorial UNED; 2016.

Niki E. Evidence for beneficial effects of vitamin E. Korean J Intern Med. 2015; 30(5): 571-579.

Fouladvand F, Falahi E, Asbaghi O, Abbasnezhad A. Effect of vitamins C and E Co-Supplementation on serum C - reactive protein Level: A systematic review and meta-Analysis of randomized controlled trials. Prev. Nutr. Food Sci. 2020, 25 (1):1-8.

Khatami PG, Soleimani A, Sharifi N, Aghadavod E, Asemi Z. The effects of high-dose vitamin E supplementation on biomarkers of kidney injury, inflammation and oxidative stress in patients with diabetic nephropathy: a randomized, double-blind, placebo-controlled trial. J Clin Lipidol. 2016, 10(4): 922-929.

Ekhlasi G, Zarrati M, Agah S, Hosseini AF, Hosseini S, Shidfar S, Soltani Aarbshahi SS, Razmpoosh E, Shidfar F. Effects of symbiotic and vitamin E supplementation on blood pressure, nitric oxide and inflammatory factors in non-alcoholic fatty liver disease. EXCLI J. 2017, 16: 278–290.

Asbaghi O, Sadeghian M, Nazarian B, Sarreshtedari M, Mozaffari-Khosravi H, Maleki V, Alizadeh M, Shokri A, Sadeghi O. The effect of vitamin E supplementation on selected inflammatory biomarkers in adults: a systematic review and meta-analysis of randomized clinical trials. Sci. Rep 2020, 10 (1):17234.

Jamalan M, Rezazadeh M, Zeinali M, Ghaffari MA. Effect of ascorbic acid and alpha-tocopherol supplementations on serum leptin, tumor necrosis factor alpha, and serum amyloid A levels in individuals with type 2 diabetes mellitus. Avicenna J Phytomed. 2015, 5(6): 531-539.

Pervez MA, Khan DA, Slehria AUR, Ijaz A. Delta-tocotrienol supplementation improves biochemical markers of hepatocellular injury and steatosis in patients with nonalcoholic fatty liver disease: A randomized, placebo-controlled trial. Complement Ther Med. 2020, 52: 1-7.

Qureshi AA, Khan DA, Mahjabeen W, Trias AM, Silswal N, Qureshi N. Impact of δ-Tocotrienol on inflammatory biomarkers and oxidative stress in hypercholesterolemic subjects. J. Clin. Exp. Cardiol. 2015, 6 (4): 2-9.

Qureshi AA, Khan DA, Mahjabeen W, Qureshi N. Dose-dependent Modulation of Lipid Parameters, Cytokines and RNA by δ-tocotrienol in hypercholesterolemic subjects restricted to AHA Step-1 Diet. JAMMR. 2015, 6(4): 351-66.

Schwab S, Zierer A, Schneider A, Heier M, Koenig W, Kastenmüller G, Waldenberger M, Peters A, Thorand B. Vitamin E supplementation is associated with lower levels of C-reactive protein only in higher dosages and combined with other antioxidants: The Cooperative Health Research in the Region of Augsburg (KORA) F4 study. Br. J. Nutr. 2015, 113(11): 1782–91.

Valisek J, Koplik R, Cejpek K. The Chemistry of Food. En: Vitamins. 2nd ed. United Kingdom: John Wiley & Sons Ltd, 2020: 386.

Combs Jr GF, McClung JP. The Vitamins. En: Vitamins needs and safety. 5th ed. United States: ELSEVIER, 2017: 104.

Publicado
2021-12-05
Cómo citar
Ventura-Pérez, P., Mateos-Islas, M., & Ariza-Ortega, J. A. (2021). Revisión del efecto de la vitamina E sobre biomarcadores inflamatorios asociados a la obesidad. Educación Y Salud Boletín Científico Instituto De Ciencias De La Salud Universidad Autónoma Del Estado De Hidalgo, 10(19), 1-8. https://doi.org/10.29057/icsa.v10i19.6889

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