Reacciones de activación C-H para preparar 2,5-di(hetero)aril furanos

Diana Castro-Castro; Daniel Mendoza-Espinosa; Alejandro Alvarez

Diana Castro-Castro Universidad Autónoma del Estado de Hidalgo https://orcid.org/0000-0001-6382-5585
Daniel Mendoza-Espinosa Universidad Autónoma del Estado de Hidalgo https://orcid.org/0000-0001-9170-588X
Alejandro Alvarez Universidad Autónoma del Estado de Hidalgo https://orcid.org/0000-0002-4937-6944

Palabras clave: activación C-H, furano, Indol, fluorescence

Resumen

En este estudio se llevó a cabo la síntesis de furanos 2,5-di(hetero)aril sustituidos mediante la doble activación C-H de furano con acetato de paladio, empleando halogenuros de (hetero)arilo y se obtuvieron rendimientos aceptables. La sustitución del furano con grupos arilo que contienen grupos electro atractores proporciona moléculas fluorescentes de bajo peso molecular con posible aplicación optoelectrónica. En cambio, la doble sustitución del furano con anillos de indol que funcionan como grupos electro donadores proporciona compuestos que prácticamente no exhiben fluorescencia.

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