Compuestos bioactivos presentes en alimentos con actividad antihipertensiva y su efecto en COVID-19

Palabras clave: Péptidos, Fenólicos, Hipertensión, COVID-19, Enzima Convertidora de Angiotensina


Los alimentos de origen natural presentan compuestos bioactivos que pueden disminuir la incidencia de enfermedades crónicas, como la hipertensión. La presión arterial alta es una de las enfermedades cardiovasculares con mayor prevalencia, la cual está regulada por el Sistema Renina Angiotensina Aldosterona. La enzima convertidora de angiotensina 2 participa en la modulación de la presión arterial, la homeostasis de la presión arterial y es el principal receptor del virus SARS-CoV-2. Entre los compuestos más estudiados se encuentran los péptidos bioactivos y los compuestos fenólicos. Los péptidos inferiores de 1 kDa y la presencia de aminoácidos hidrofóbicos son los mejores candidatos para inhibir la enzima convertidora de angiotensina (ECA). Los compuestos fenólicos como los ácidos fenólicos y flavonoides son capaces de inhibir la ECA al reducir el estrés oxidativo implicado en la patogenia de la hipertensión. Este trabajo presenta una síntesis crítica sobre el efecto de los compuestos bioactivos en la  ECA, la hipertensión y su relación con el COVID-19.


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Cómo citar
Garcia-Castro, A., Roman-Gutierrez, A. D., Guzmán-Ortiz, F. A., Castañeda-Ovando, A., & Cariño-Cortés, R. (2022). Compuestos bioactivos presentes en alimentos con actividad antihipertensiva y su efecto en COVID-19. Pädi Boletín Científico De Ciencias Básicas E Ingenierías Del ICBI, 9(18), 1-6.

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