Saliva as an alternative diagnostic test in the detection of COVID-19
Abstract
The World Health Organization (WHO) announced that the 2019 coronavirus disease (COVID-19) epidemic, originating in Wuhan, China, has become a major public health challenge of international concern not only to China but also for countries around the world, within the clinical manifestations of this disease, fever, dry cough and dyspnoea have been reported as the most prevalent, followed by myalgia, sputum, sore throat, headache, diarrhea and general malaise; in connection with the current emergency situation, it is very important to prepare rapid and accurate diagnostic test methods for SARS-CoV-2 for the identification of suspected patients with the aim of controlling the outbreak in the community and in hospitals; recent studies have shown that saliva could be a valuable sample for diagnosis considered as a non-invasive procedure that has adequate precision and reliability regarding the detection of SARS-CoV-2 according to the RT-PCR technique, which makes it a valid alternative for the diagnosis and monitoring of the SARS-CoV-2 viral load, providing a cost-effective and convenient platform, with a relatively minimal risk of cross infection, thus considering it as an ideal diagnostic biofluid.
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