Péptidos bioactivos como anticancerígenos y antimicrobianos

Shanty Itzel Olguín-Vargas; Tamara Elena Gutiérrez-Nava; Eduardo Antonio Quezada-Maravilla; Juan Ocampo-López; Diana Patricia Carreón Camacho; Armando Zepeda Bastida

doi:10.29057/icap.v12i23.15431

Autores/as

Shanty Itzel Olguín-Vargas Instituto de Ciencias Agropecuarias https://orcid.org/0009-0007-1051-6923
Tamara Elena Gutiérrez-Nava Instituto de Ciencias Agropecuarias https://orcid.org/0009-0006-7423-4805
Eduardo Antonio Quezada-Maravilla Instituto de Ciencias Agropecuarias https://orcid.org/0009-0008-8290-5829
Juan Ocampo-López Instituto de Ciencias Agropecuarias https://orcid.org/0000-0002-9208-7216
Diana Patricia Carreón Camacho Instituto de Ciencias Agropecuarias https://orcid.org/0000-0001-9259-9943
Armando Zepeda Bastida Instituto de Ciencias Agropecuarias https://orcid.org/0000-0003-0572-5206

DOI:

https://doi.org/10.29057/icap.v12i23.15431

Palabras clave:

Péptido antibacteriano, Péptido modificado, Terapia contra cáncer, Cepas

Resumen

Los microorganismos son las formas de vida más abundantes en el planeta, siendo muchos de ellos potencialmente patógenos para otros seres vivos. Tanto plantas como animales han evolucionado combatiendo el ataque constante de microorganismos mediante el desarrollo de sistemas de defensa que varían en complejidad de acuerdo al grado evolutivo del organismo. En los últimos años se han descrito diversas moléculas efectoras de la respuesta innata dentro de las que se encuentran las proteínas de bajo peso molecular, conocidas como péptidos antimicrobianos, aunque combaten un amplio espectro de microorganismos, debido a su mecanismo de acción, estos péptidos no afectan a las células eucariotas, portal motivo, los péptidos antimicrobianos se están estudiando intensamente y se están ensayando como agentes antimicrobianos para la aplicación biotecnológica como agentes terapéuticos. Aquí, se realizó una revisión de aquellos péptidos bioactivos con actividad antimicrobiana y anticancerígena para su potencial uso.

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Citas

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