Fagoterapia en perros y gatos: evidencia experimental y clínica
DOI:
https://doi.org/10.29057/icap.v13iEspecial.17927Palabras clave:
Fagoterapia, infecciones multirresistentes, resistencia antimicrobiana, One healthResumen
La resistencia antimicrobiana (RAM) representa una amenaza creciente para la salud pública y veterinaria, agravada por el uso intensivo de antibióticos en animales de compañía. Debido a la estrecha convivencia humano-animal, perros y gatos pueden actuar como reservorios de bacterias multirresistentes bajo el enfoque One Health. Ante la limitada disponibilidad de nuevos antimicrobianos, la fagoterapia surge como una alternativa terapéutica de precisión. El presente artículo revisa evidencia in vitro, ensayos clínicos y casos de éxito sobre el uso de bacteriófagos en perros y gatos. Los estudios analizados muestran resultados favorables frente a infecciones causadas por Pseudomonas aeruginosa y Staphylococcus pseudintermedius, incluyendo altas tasas de lisis bacteriana, recuperación tisular y reducción de recaídas clínicas. Además, se documenta una importante sinergia entre fagos y antibióticos, así como una mínima alteración de la microbiota comensal. Se concluye que la fagoterapia posee potencial para el tratamiento de infecciones bacterianas multirresistentes en medicina veterinaria, especialmente en patologías crónicas refractarias a los tratamientos convencionales.
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Derechos de autor 2026 Martin Talavera-Rojas , Misael Angeles-González, Sandra Blas-Yáñez, Nydia Edith Reyes-Rodríguez, Vicente Vega-Sánchez, Juan Martín Talavera-González
Esta obra está bajo una licencia internacional Creative Commons Atribución-NoComercial-SinDerivadas 4.0.
