Mentha piperita L. extracts obtained by hybrid technology
Abstract
Mentha piperita L. is one of the most popular and consumed species worldwide thanks to the presence of properties of great interest such as: antioxidant, antifungal and antibacterial capacity. There are various methodologies for the extraction of secondary metabolites, however, many of them turn out to be inefficient since they present considerable extraction times, low yields, and high costs. In this work, a hybrid extraction methodology was developed using ultrasound-microwave assistance to obtain secondary metabolites from dry leaves of Mentha piperita L. The results were compared with conventional extraction techniques, highlighting a considerable reduction in time and a yield of 23.58%, this being on average 7.56% higher than the results obtained by conventional techniques. In addition, by means of FTIR-ATR and HPLC-MS/ESI, organic compounds were identified, such as caffeic acid, medioresinol, caffeoylquinic acids, rosmarinic acid and luteolin, demonstrating that the hybrid ultrasound-microwave technology is a viable alternative to extract compounds of interest with excellent returns.
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Alirezalu, K., Pateiro, M., Yaghoubi, M., Alirezalu, A., Peighambardoust, S. H., & Lorenzo, J. M. (2020). Phytochemical constituents, advanced extraction technologies and techno-functional properties of selected Mediterranean plants for use in meat products. A comprehensive review. Trends in Food Science & Technology, 100, 292-306. https://doi.org/10.1016/j.tifs.2020.04.010
Ascacio-Valdés, J.A., Aguilera-Carbó, A.F., Buenrostro, J.J., Prado-Barragán, A., Rodríguez-Herrera, R. and Aguilar, C.N. (2016). The complete biodegradation pathway of ellagitannins by Aspergillus niger in solid-state fermentation. J. Basic Microbiol., 56: 329-336. https://doi.org/10.1002/jobm.201500557
Barreto-Campoverde K. L. Evaluación de plantas y extractos, repelentes de insectos en el cultivo de tomate (Solanum lycopersicum) milagro–guayas. Universidad Agraria del Ecuador. Milagro. (2019). [En línea]. Revisado el 30-08-22. https://cia.uagraria.edu.ec/Archivos/BARRETO%20CAMPOVERDE%20KATY%20LIZ.pdf
Beigi, M., Torki-Harchegani, M., & Pirbalouti, A. G. (2018). Quantity and chemical composition of essential oil of peppermint (Mentha×piperita L.) leaves under different drying methods. International Journal of Food Properties, 21(1), 267–276. https://doi.org/10.1080/10942912.2018.1453839
Benabdallah, A., Boumendjel, M., Aissi, O., Rahmoune, C., Boussaid, M., & Messaoud, C. (2018). Chemical composition, antioxidant activity and acetyl cholinesterase inhibitory of wild Mentha species from Northeastern Algeria. South African Journal of Botany, 116, 131–139. https://doi.org/10.1016/j.sajb.2018.03.002
Dolzhenko, Y., Bertea, C. M., Occhipinti, A., Bossi, S., & Maffei, M. E. (2010). UV-B modulates the interplay between terpenoids and flavonoids in peppermint (Mentha × piperita L.). Journal of Photochemistry and Photobiology B: Biology, 100, 67–75. https://doi.org/10.1016/j.jphotobiol.2010.05.003
Damien-Dorman, H. J., Koşar, M., C-Başer, K. H., & Hiltunen, R. (2009). Phenolic profile and antioxidant evaluation of Mentha x piperita L. (peppermint) extracts. Natural Product Communications, 4(4), 535–542. https://doi.org/10.1177/1934578X0900400419
Farnad, N., Heidari, R., & Aslanipour, B. (2014). Phenolic composition and comparison of antioxidant activity of alcoholic extracts of peppermint (Mentha piperita). Food Measure, 8, 113–121. https://doi.org/10.1007/s11694-014-9171-x
Garcia-Ortiz, J. D., Flores-Gallegos, A. C., Ascacio-Valdés, J. A., López-Badillo, C. M., Nery-Flores, S. D., Esparza-González, S. C., & Rodríguez-Herrera, R. (2022). Microwave-ultrasound assisted extraction of red corn pigments and their effect on chemical composition and Tecno-functional properties. Food Bioscience, 102115. https://doi.org/10.1016/j.fbio.2022.102115
Gholamipourfard, K., Salehi, M., & Banchio, E. (2021). Mentha piperita phytochemicals in agriculture, food industry and medicine: Features and applications. South African Journal of Botany, 141, 183-195. https://doi.org/10.1016/j.sajb.2021.05.014
Gordo, D. A. M. (2018). Los compuestos fenólicos, un acercamiento a su biosíntesis, síntesis y actividad biológica. Revista de investigación agraria y ambiental, 9(1), 81-104. https://doi.org/10.22490/21456453.1968
Guedon, D. J., & Pasquier, B. P. (1994). Analysis and distribution of flavonoid glycosides and rosmarinic acid in Mentha × piperita clones. Journal of Agricultural and Food Chemistry, 42, 679–684. https://doi.org/10.1021/jf00039a015
Inoue, T., Sugimoto, Y., Masuda, H., & Kamei, C. (2002). Antiallergic effect of flavonoid glycosides obtained from Mentha piperita L. Biological and Pharmaceutical Bulletin, 25(2), 256–259. https://doi.org/10.1248/bpb.25.256
Mohsen-Nia, M., Amiri, H. & Jazi, B. Dielectric Constants of Water, Methanol, Ethanol, Butanol and Acetone: Measurement and Computational Study. Journal of Solution Chemistry, 39, 701–708 (2010). https://doi.org/10.1007/s10953-010-9538-5
Mojall, M., Sharmin, E., Obaid, N.A., Alhindi, Y., Abdall, A.N. (2022) Polyvinyl alcohol/corn starch/castor oil hydrogel films, loaded with silver nanoparticles biosynthesized in Mentha piperita leaves’ extract. Journal of King Saud University–Science, 34, 101879. https://doi.org/10.1016/j.jksus.2022.101879
Mekinic, I. G., Skroza, D., Ljubenkov, I., Simat, V., Mozina, S. S., & Katalinic, V. (2014). In vitro antioxidant and antibacterial activity of Lamiaceae phenolic extracts: A correlation study. Food Technology and Biotechnology, 52(1), 119–127. https://hrcak.srce.hr/118571
Mendez-Flores, A., Hérnandez-Almanza, A., Sáenz-Galindo, A., Morlett-Chávez, J., Aguilar, C. N., & Ascacio-Valdés, J. (2018). Ultrasound-assisted extraction of antioxidant polyphenolic compounds from Nephelium lappaceum L. (Mexican variety) husk. Asian Pacific Journal of Tropical Medicine, 11(12), 676. https://doi.org/10.4103/1995-7645.248339
Neira, M. C., Jiménez, F., & D'León, L. F. P. (1980). Influencia de la constante dieléctrica en la solubilización del diazepam. Revista Colombiana de Ciencias Químico-Farmacéuticas, 3(4), 37-61. https://doi.org/10.15446/rcciquifa
Nilo, M. C. S., Riachi, L. G., Simas, D. L. R., Coelho, G. C., da Silva, A. J. R., Costa, D. C. M., De Maria, C. A. B. (2017). Chemical composition, antioxidant, antifungal properties of Mentha x piperita L. (Peppermint), and Mentha arvensis L. (cornmint) samples. Food Research, 1(5), 147–156. https://www.myfoodresearch.com/uploads/8/4/8/5/84855864/_2__fr-2017-104_nilo_4.pdf
Pramila, D. M., Xavier, R., Marimuthu, K., Kathiresan, S., Khoo, M. L., Senthilkumar, M., & Sreeramanan, S. (2012). Phytochemical analysis and antimicrobial potential of methanolic leaf extract of peppermint (Mentha piperita: Lamiaceae). Journal of Medicinal Plants Research, 6(2), 331-335. https://doi.org/10.5897/JMPR11.1232
Roshanpour, S., Tavakoli, J., Beigmohammadi, F., Alaei, S., & Mousavi Khaneghah, A. (2021). Extraction of phenol compound from Mentha piperita by ultrasonic waves based on a response surface methodology. Food Science & Nutrition. https://doi.org/10.1002/fsn3.2467
Rubio Garza, M. F. (2019). Evaluación in vitro antimicrobiana y coagulante de los extractos etanólicos de Heterotheca inuloides, Mentha piperita y Amphyptergium adstringens como alternativa terapéutica en Odontopediatría (Doctoral dissertation, Universidad Autónoma de Nuevo León). [En línea] Revisado el 24/11/2022 en: http://eprints.uanl.mx/id/eprint/18697
Salehi, B., Stojanovic-Radic, Z., Matejic, J., Sharopov, F., Antolak, H., Kregiel, D., Sharifi-Rad, J. (2018). Plants of genus Mentha: From farm to food factory. Plants, 7, 70. 1-36. https://doi.org/10.3390/plants7030070.
Simić, V. M., Rajković, K. M., Stojičević, S. S., Veličković, D. T., Nikolić, N. Č., Lazić, M. L., & Karabegović, I. T. (2016). Optimization of microwave-assisted extraction of total polyphenolic compounds from chokeberries by response surface methodology and artificial neural network. Separation and Purification Technology, 160, 89-97. https://doi.org/10.1016/j.cep.2019.01.006
Copyright (c) 2023 Yesenia Damaris Franco-Aguirre, Aidé Sáenz-Galindo, Claudia Magdalena López-Badillo, Raúl Rodríguez-Herrera, Adalí Oliva Castañeda-Facio, Juan Alberto Ascacio-Valdés
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