Análisis Fractal del Electroencefalograma Durante la Vigilia en Reposo de Adultos Mayores Hidalguenses y Deterioro Cognitivo

Erika Rodriguez-Torres; Alejandra Rosales-Lagarde; Carlos Fernando  Chávez Vega; José Luis  Ocaña Garrido; Yair Alejandro  Pardo Rosales; Rodrigo  Silva Mota

doi:10.29057/icbi.v7i14.4334

Erika E Rodriguez-Torres Universidad Autónoma del Estado de Hidalgo https://orcid.org/0000-0002-7738-1863
Alejandra Rosales-Lagarde Instituto Nacional de Psiquiatría Ramón de la Fuente Muñiz
Carlos Fernando Chávez Vega Universidad Autónoma del Estado de Hidalgo
José Luis Ocaña Garrido Universidad Autónoma del Estado de Hidalgo
Yair Alejandro Pardo Rosales Universidad Autónoma del Estado de Hidalgo
Rodrigo Silva Mota Universidad Autónoma del Estado de Hidalgo

DOI: https://doi.org/10.29057/icbi.v7i14.4334

Keywords: time series, fractal, hurst exponent, mild cognitive impairment, elderly

Abstract

It is known that the Detrended Fluctuations Analysis or DFA of biological time series like the Electrocardiogram (ECG), the Electroencephalogram (EEG) and others, turns out to be a useful tool to discriminate between health or illness. In order to corroborate if there are differences between the DFA of Older Adults (OAs) with Cognitive Impairment (CI) and without Cognitive Impairment (wCI), DFAs were performed in two subjects, each of them diagnosed with CI or wCI. EEG and Electromyography (EMG) records were obtained during the closed-eyes condition. A friendly interface was developed in Python that was used for the calculation of DFAs of selected time series. It was observed that at rest with closed eyes, the subject with CI has higher values in frontal regions than the subject wCI. It is concluded that the DFA provides quantifiable information on the location and mechanisms underlying the CI that can serve to help to monitor the course of CI in OAs.

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Author Biography

Erika E Rodriguez-Torres, Universidad Autónoma del Estado de Hidalgo

She finished her PhD in Sciences under the tutelage of Dr. Pablo Rudomín Zevnovaty in 2013. Dr. Rodriguez-Torres is a member of the National System of Researchers since 2014, level I. She has more than 20 research articles, dissemination and book chapters. Participation in national and international congresses. More than 10 undergraduate and master's degree students. The 90% of her students continue with postgraduate studies in high quality programs. Her interests are problems in the area of neurosciences such as spinal cord injuries, malnutrition, cognitive deterioration, etc. analyzing these with the help of mathematical and computational tools.

References

Peng, C. K., Buldyrev, S. V., Havlin, S., Simons, M., Stanley, H. E., & Goldberger, A. L. (1994). Mosaic organization of DNA nucleotides. Physical review e, 49(2), 1685.

Rodríguez EE, Hernández-Lemus E, Itzá-Ortiz BA, Jiménez I, Rudomín P. (2011). Multichannel Detrended Fluctuation Analysis Reveals Synchronized Patterns of Spontaneous Spinal Activity in Anesthetized Cats. PLoS ONE 6(10): e26449. doi:10.1371/journal.pone.0026449

Rosales-Lagarde, A., Rodriguez-Torres, E. E., Itzá-Ortiz, B. A., Miramontes, P., Vázquez-Tagle, G., Enciso-Alva, J. C., & Lopez-Noguerola, J. S. (2018). The Color of Noise and Weak Stationarity at the NREM to REM sleep transition in Mild Cognitive Impaired subjects. Frontiers in psychology, 9.

Secretaría de Salud, Instituto Nacional de Geriatría, Instituto Nacional de Neurología y Neurocirugía Manuel Velasco Suárez, Instituto Nacional de Psiquiatría Ramón de la Fuente Muñiz, Instituto Nacional de las Personas Adultas Mayores, Federación Mexicana de Alzheimer. (2014). Plan de Acción Alzheimer y otras demencias. México.