Estructura cristalina de hidroxiapatita presente en el fémur de rata wistar con diabetes inducida

Gabriel Herrera-Pérez; Victor Ivan Landeros-Velazquez; Esmeralda Rodriguez-Miranda; Rafael Vargas-Bernal

doi:10.29057/icbi.v10i20.9967

Gabriel Herrera-Pérez Instituto Tecnológico Superior de Irapuato https://orcid.org/0000-0001-9770-5952
Victor Ivan Landeros-Velazquez Instituto Tecnológico Superior de Irapuato https://orcid.org/0000-0003-0693-9732
Esmeralda Rodriguez-Miranda Universidad de Guanajuato Campus León https://orcid.org/0000-0003-3551-7344
Rafael Vargas-Bernal Instituto Tecnológico Superior de Irapuato https://orcid.org/0000-0003-4865-4575

DOI: https://doi.org/10.29057/icbi.v10i20.9967

Keywords: Hydroxyapatite, Hydroxyapatite-Carbonated, X-Ray Difraction, Rietveld Refinement

Abstract

Bone is a tissue that is classified as a composite material. In living beings, bones, in addition to having a structural function, are also a storage site for minerals. The basic structure of bone is procollagen units and hydroxyapatite crystals, the latter with both atomic (Na⁺¹, K⁺¹, Mg⁺², Ca⁺², F^-1, Cl^-1) and molecular (CO₃^-2) ion substitutions. The ionic substituents vary according to the environment of the bone and some diseases such as diabetes can affect the substitution. In this work, the x-ray diffraction patterns of femurs extracted from wistar rats with induced diabetes are reported. In these diffractograms, differences were observed in the main signal (211), so the rietveld refinement was used to identify the crystalline phases for their quantitative estimation. The results show the effect of induced diabetes on the quality of hydroxyapatite.

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