Genetic predisposition and risk factors associated with Neuroblastoma

Keywords: mutation, neuroblastoma, chromosome instability, oncology, solid tumor

Abstract

Tumors derived from the neural crest such as Neuroblastoma have increased their incidence in the last decade; therefore, currently in Mexico, they represent a great challenge in Pediatric Oncology due to the high mortality rate in newborns who suffer from it, since this tumor is characterized for being the most frequent solid extracranial tumor in childhood and has a low survival rate. The present study is based on updated scientific review sources where the aim is to update and disseminate the main genetic, chemical or environmental risk factors that intervene etiologically in the production of chromosomal instability that could trigger the presence of neuroblastoma to prevent pre conceptional maternal exposure to this type of factors and prevent the number of cases from continuing to increase. 

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Published
2022-01-05
How to Cite
Hernández-Rosalio, L. (2022). Genetic predisposition and risk factors associated with Neuroblastoma. XIKUA Boletín Científico De La Escuela Superior De Tlahuelilpan, 10(19), 38-41. https://doi.org/10.29057/xikua.v10i19.8119